Anakinra is a biologic medication used to treat rheumatoid arthritis and other inflammatory diseases.
A CD30-directed antibody-drug conjugate called brentuximab vedotin is used to treat different lymphomas.
For adults with few other treatment options, the drug cefiderocol has been developed to treat infections brought on by aerobic Gram-negative organisms that are multi-drug (MDR) or extensively drug (XDR) resistant.
The antiapoptotic protein BCL-2 is selectively and orally bioavailability inhibited by the small molecule Venetoclax. It has been shown that overexpression of BCL-2 in CLL cells mediates tumor cell survival.