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Kineret (Anakinra)

Brand Name: KINERET
Active Ingredient: Anakinra
Dosage Form: 100 mg/0.67 mL solution for subcutaneous injection
Manufacturer Name: Swedish Orphan Biovitrum AB

For the treatment of Still’s disease, including Systemic Juvenile Idiopathic Arthritis (SJIA) and Adult-Onset Still’s Disease (AOSD), with active systemic features of moderate to high disease activity, or in patients with ongoing disease activity after treatment with non-steroidal anti-inflammatory drugs (NSAIDs) or glucocorticoids, Kineret is indicated in adults, adolescents, children, and infants aged eight months and older with a body weight of 10.

It is possible to administer Kineret alone or in combination with other anti-inflammatory medications and disease-modifying antirheumatic medications (DMARDs). The FDA-approved treatment for the neonatal-onset multisystem inflammatory disease (NOMID), a type of cryopyrin-associated periodic syndromes, in both children and adults is Kineret.

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Doctor

Why is Kineret injection prescribed?

The prescription medicine KINERET (anakinra), commonly known as an interleukin-1 receptor antagonist (IL-1Ra), is only available to adults over the age of 18 to:

  • Reduce the signs and symptoms of moderate to severe active rheumatoid arthritis (RA) and slow the damage it causes.
  • To treat people with a form of Cryopyrin-Associated Periodic Syndromes (CAPS) called Neonatal-Onset Multisystem Inflammatory Disease (NOMID)
  • To treat people with Deficiency of Interleukin-1 Receptor Antagonist (DIRA)

To administer Kineret, a subcutaneous injection is used.

Kineret is provided in a graduated prefilled syringe and is ready for use. Using the graduated prefilled syringe, doses between 20 and 100 mg are possible. The syringe is inappropriate for pediatric patients with a body weight below 10 kg because the minimum dose is 20 mg.

Who should not take KINERET?

  • Individuals with allergies to proteins produced by the E. coli bacteria.
  • Individuals with allergies to any component of KINERET, including anakinra. A complete list of KINERET's ingredients can be seen at the end of the patient information sheet.
  • Women who are pregnant or breastfeeding.

If you’re unsure, speak with your doctor.

What are the possible side effects of KINERET?

Severe possible side effects of KINERET include:

  • Allergic reactions
  • Fever or chills
  • Headache
  • Nausea and Vomiting
  • Diarrhea
  • Joint pain
  • Fever
  • Feeling like you have the flu
  • Sore throat or runny nose
  • Sinus infection
  • Redness, Bruising, Swelling, and Pain
  • Urinary tract infection
  • Pain in your stomach area

What documents are required to import KINERET to Dubai?

Individual Patients or hospitals may import Kineret 100 mg at a reasonable price
The following paperwork is necessary to import:
  • An authentic prescription from a licensed physician.
  • Diagnostic reports for patients
  • Patients id proof (Certificate of Origin)

Special Precautions For Kineret

  • Anakinra is sold in graduated prefilled syringes at a reasonable injection cost.
  • Kineret is a sterile, unpreserved fluid. For one use only.
  • Keep in the refrigerator at 2 to 8 degrees Celsius.
  • Avoid freezing.
  • To protect against light, keep it in the original container.
  • The prefilled syringe shouldn't be shaken.
  • For ambulatory use, Kineret may be left out of the fridge for up to 12 hours at a temperature no higher than 25 °C without going past the expiration date.
  • The product must be thrown off once this time has passed instead of returning it to the refrigerator.
  • Before using the solution, visually inspect it for contaminants and discolouration.
  • It is only advised to inject transparent, colourless to white solutions that may contain a few translucent to white amorphous particles from the substance itself.
  • The existence of these particles has no impact on the product's quality.
  • Following local legislation, waste and unneeded pharmaceuticals should be disposed of.

About Us

We are a leading pharmaceutical wholesaler, Hayat Alhikmah, situated in Dubai. By providing generic medications, reference listed drugs, name patient import services, and temperature-controlled products simple to access for our consumers, we help them overcome geographic distances.

We offer affordable access to anakinra injection in Dubai with ease and speed. Depending on the customer’s needs, we provide a quality guarantee and shipping anywhere in the world.

Please schedule a consultation with us by calling us at +971 54 777 1238 or +971 55 223 1090 or email us at [email protected] to know how much anakinra injection costs in Dubai. Our helpful team would be happy to assist you and provide any general or medical information.
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FAQ's

A prescription drug called Kineret, also known as an interleukin-1 receptor antagonist, is used to treat Neonatal-Onset Multisystem Inflammatory Disease and Cryopyrin-Associated Periodic Syndromes as well as the signs and symptoms of rheumatoid arthritis. You might only need to use part of the liquid medication in the prefilled syringe. Your healthcare professional will determine the best Kineret dosage for you or your child. Kineret is injected beneath the skin. Inject Kineret every day at roughly the same time. Your doctor may need to modify how frequently you receive Kineret injections if you have renal issues. To determine when to administer your next injection of Kineret if you miss a dosage, consult your healthcare professional.

Anakinra, an interleukin-1 receptor antagonist, is the substance that makes up Kineret. You will inject the solution under your skin, provided in a prefilled syringe. A biologic drug is kineret. A biologic is created from pieces of living things. Only the brand-name medication Kineret is sold alongside anakinra. It is not offered as a biosimilar medication. Kineret can help treat moderate to severe RA symptoms and stop the disease’s development. Before using Kineret, you must have tried a different RA medicine known as a disease-modifying antirheumatic drug. Kineret is also used to treat interleukin-1 receptor antagonist deficiency. To cure DIRA, Kineret blocks a protein present in various bodily tissues and organs.

The drug anakinra is a member of the immune modulatory agent drug class. Anakinra is used to lessen erosions and cartilage breakdown, which helps to reduce the joint damage brought on by rheumatoid arthritis. This is accomplished by interleukin-1 protein activity being reduced when the immune system is being targeted. Patients taking anakinra frequently inquire about the expected time of results. Patients will respond to treatment in varying amounts of time. Some people may experience anakinra’s effects quickly and see improvement within the first month. However, it usually takes three to six months for individuals to benefit from the medicine fully. To get better results, you need to follow the doctor’s opinion. 

Anakinra, the medication’s primary ingredient, suppresses the immune system. It is a drug that lessens the immune system’s activity. It is a replica of the human protein known as human interleukin 1 receptor antagonist, which blocks the receptors for the chemical messenger interleukin 1 in the body. The inflammation and joint damage caused by rheumatoid arthritis patients’ elevated levels of this messenger are also responsible for the inflammation linked to CAPS, familial Mediterranean fever, and Still’s illness. Anakinra reduces the symptoms of these diseases by binding to the receptors where interleukin 1 would typically attach itself. This prevents interleukin 1 from acting as it would otherwise.

The FDA has given Anakinra approval to treat rheumatoid arthritis, interleukin-1 antagonist deficiency, and neonatal-onset multisystem inflammatory illness. Even though it is not an FDA-approved application, anakinra is occasionally used to treat gout, adult-onset still a disease, systemic juvenile idiopathic arthritis, and other auto-inflammatory diseases. Before use, anakinra must be brought to room temperature from a refrigerator where it will be kept. A nurse or doctor may teach patients how to administer the injections. It generally helps to have a partner or buddy when learning how to administer the shots. The front of the thigh or abdomen can be injected with anakinra. Rotating injection sites will prevent the same site from being utilised repeatedly.

The prescription medicine KINERET (anakinra), commonly known as an interleukin-1 receptor antagonist (IL-1Ra), is only available to adults over the age of 18 to:

  •  Reduce the signs and symptoms of moderate to severe active rheumatoid arthritis (RA) and slow the damage it causes.
  •  To treat people with a form of Cryopyrin-Associated Periodic Syndromes (CAPS) called Neonatal-Onset Multisystem Inflammatory Disease (NOMID)
  •  To treat people with Deficiency of Interleukin-1 Receptor Antagonist (DIRA)

 

Kineret is provided in a graduated prefilled syringe and is ready for use. Using the graduated prefilled syringe, doses between 20 and 100 mg are possible. The syringe is inappropriate for pediatric patients with a body weight below 10 kg because the minimum dose is 20 mg.

  •  Individuals with allergies to proteins produced by the E. coli bacteria.
  •  Individuals with allergies to any component of KINERET, including anakinra. A complete list of KINERET’s ingredients can be seen at the end of the patient information sheet.
  •  Women who are pregnant or breastfeeding.
If you’re unsure, speak with your doctor.

Severe possible side effects of KINERET include:

  •  Allergic reactions
  •  Fever or chills
  •  Headache
  •  Nausea and Vomiting
  •  Diarrhea
  •  Joint pain
  •  Fever
  •  Feeling like you have the flu
  •  Sore throat or runny nose
  •  Sinus infection
  •  Redness, Bruising, Swelling, and Pain
  •  Urinary tract infection
  •  Pain in your stomach area
Individual Patients or hospitals may import Kineret 100 mg at a reasonable price
The following paperwork is necessary to import:
  •  An authentic prescription from a licensed physician.
  •  Diagnostic reports for patients
  •  Patients id proof (Certificate of Origin)
 
  •   Anakinra is sold in graduated prefilled syringes at a reasonable injection cost.
  •  Kineret is a sterile, unpreserved fluid. For one use only.
  •  Keep in the refrigerator at 2 to 8 degrees Celsius.
  •  Avoid freezing.
  •  To protect against light, keep it in the original container.
  •  The prefilled syringe shouldn’t be shaken.
  • For ambulatory use, Kineret may be left out of the fridge for up to 12 hours at a temperature no higher than 25 °C without going past the expiration date.
  •  The product must be thrown off once this time has passed instead of returning it to the refrigerator.
  •  Before using the solution, visually inspect it for contaminants and discolouration.
  •  It is only advised to inject transparent, colourless to white solutions that may contain a few translucent to white amorphous particles from the substance itself.
  •  The existence of these particles has no impact on the product’s quality.
  •  Following local legislation, waste and unneeded pharmaceuticals should be disposed of.

Three years.